Identification of the First Oomycete Mating-type Locus Sequence in the Grapevine Downy Mildew Pathogen, Plasmopara viticola
Type de document
journalArticle
Langue source
-- Langue source --
Titre
Identification of the First Oomycete Mating-type Locus Sequence in the Grapevine Downy Mildew Pathogen, Plasmopara viticola
Titre français
Titre anglais
Auteur(s)
- DUSSERT Yann
- LEGRAND Ludovic
- MAZET Isabelle D.
- COUTURE Carole
- PIRON Marie-Christine
- SERRE Rémy-Félix
- BOUCHEZ Olivier
- MESTRE Pere
- TOFFOLATTI Silvia Laura
- GIRAUD Tatiana
- DELMOTTE François
Editeur(s)
Autre(s)
Id
DQIK7AXC
Version
3048
Date ajout
2 avril 2021 17:44
Date modification
2 avril 2021 17:45
Résumé
Mating types are self-incompatibility systems that promote outcrossing in plants, fungi, and oomycetes. Mating-type genes have been widely studied in plants and fungi but have yet to be identified in oomycetes, eukaryotic organisms closely related to brown algae that cause many destructive animal and plant diseases. We identified the mating-type locus of Plasmopara viticola, the oomycete responsible for grapevine downy mildew, one of the most damaging grapevine diseases worldwide. Using a genome-wide association approach, we identified a 570-kb repeat-rich non-recombining region controlling mating types, with two highly divergent alleles. We showed that one mating type was homozygous, whereas the other was heterozygous at this locus. The mating-type locus encompassed 40 genes, including one encoding a putative hormone receptor. Functional studies will, however, be required to validate the function of these genes and find the actual determinants of mating type. Our findings have fundamental implications for our understanding of the evolution of mating types, as they reveal a unique determinism involving an asymmetry of heterozygosity, as in sex chromosomes and unlike other mating-type systems. This identification of the mating-type locus in such an economically important crop pathogen also has applied implications, as outcrossing facilitates rapid evolution and resistance to harsh environmental conditions.
Note
None
CRAW tags
- AB - Transversal
- FREDO biologie des nuisibles
- FREDO santé végétale
- GEO France
- GEO Global
- maladie
- viticulture
WEB tags
- mating-type
- oomycetes
- self-incompatibility system
- stramenopiles
Titre de la publication
Current Biology
Volume
30
Pages
3897-3907.e4
Date caractères
October 19, 2020
Date publication
19 octobre 2020
Doi
10.1016/j.cub.2020.07.057
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Issn
0960-9822
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